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Dental restoration / Published data reanalysis

See source summaries and sensitivity

Aged interface data still lack measured repair-depth linkage

Source blocks lack tooth IDs. OCT enhanced-signal width is a proxy, thermal cycling is distinct from mechanical fatigue, and separate tensile records cannot be joined to nominal repair depth.

Source: studies/checklist-integration-2026-10-19/materials/results.json
SHA-256 of UTF-8 text with LF line endings: cf50b605932a42f2b77d93df387023e604b8a764fddeccc47ff2297a59003cb8

{
  "scope": "Post-thermal-cycle established-restorative dentin-interface benchmark, not enamel regrowth",
  "group_summaries": [
    {
      "group": "ER",
      "n_source_scan_rows": 50,
      "source_row_mean_percent": 34.34646,
      "source_row_median_percent": 35.87,
      "source_row_sample_sd_percent_not_independent_tooth_sd": 7.487504238586923,
      "source_row_range_percent": [
        18.153,
        47.043
      ],
      "conditional_block_as_tooth_summary": {
        "n_worksheet_blocks": 5,
        "block_means_percent": [
          40.0276,
          39.881099999999996,
          27.4146,
          30.5915,
          33.8175
        ],
        "mean_percent": 34.34646,
        "sample_sd_of_block_means_percent": 5.597718239872385,
        "qualification": "Conditional worksheet-block nesting sensitivity; paper reports five teeth and ten scans per tooth, but no individual identity crosswalk is present. No donor count or independent replication is inferred from row blocks."
      },
      "leave_one_source_block_out_means_percent": [
        32.926175,
        32.9628,
        36.079425,
        35.285199999999996,
        34.478699999999996
      ],
      "leave_one_block_out_range_percent": [
        32.926175,
        36.079425
      ],
      "repeated_runs_at_least_three_values": [
        {
          "length": 7,
          "left_source_cells": [
            "A13",
            "A14",
            "A15",
            "A16",
            "A17",
            "A18",
            "A19"
          ],
          "right_source_cells": [
            "A46",
            "A47",
            "A48",
            "A49",
            "A50",
            "A51",
            "A52"
          ],
          "interpretation": "Exact repeated values retained. Could reflect measurement coincidence, reuse or transcription; source identity records are needed, and no cause is assigned."
        }
      ]
    },
    {
      "group": "ER/CHX",
      "n_source_scan_rows": 50,
      "source_row_mean_percent": 33.50206,
      "source_row_median_percent": 31.610999999999997,
      "source_row_sample_sd_percent_not_independent_tooth_sd": 6.95771108389381,
      "source_row_range_percent": [
        22.933,
        52.342
      ],
      "conditional_block_as_tooth_summary": {
        "n_worksheet_blocks": 5,
        "block_means_percent": [
          40.5873,
          30.4289,
          33.6463,
          34.5348,
          28.313
        ],
        "mean_percent": 33.50206,
        "sample_sd_of_block_means_percent": 4.681309619433434,
        "qualification": "Conditional worksheet-block nesting sensitivity; paper reports five teeth and ten scans per tooth, but no individual identity crosswalk is present. No donor count or independent replication is inferred from row blocks."
      },
      "leave_one_source_block_out_means_percent": [
        31.73075,
        34.27035,
        33.466,
        33.243875,
        34.799325
      ],
      "leave_one_block_out_range_percent": [
        31.73075,
        34.799325
      ],
      "repeated_runs_at_least_three_values": []
    },
    {
      "group": "SE",
      "n_source_scan_rows": 50,
      "source_row_mean_percent": 27.29802,
      "source_row_median_percent": 27.219,
      "source_row_sample_sd_percent_not_independent_tooth_sd": 8.637869846749703,
      "source_row_range_percent": [
        14.235,
        44.602
      ],
      "conditional_block_as_tooth_summary": {
        "n_worksheet_blocks": 5,
        "block_means_percent": [
          27.7717,
          26.3155,
          25.5025,
          30.3672,
          26.5332
        ],
        "mean_percent": 27.29802,
        "sample_sd_of_block_means_percent": 1.8985801186676319,
        "qualification": "Conditional worksheet-block nesting sensitivity; paper reports five teeth and ten scans per tooth, but no individual identity crosswalk is present. No donor count or independent replication is inferred from row blocks."
      },
      "leave_one_source_block_out_means_percent": [
        27.1796,
        27.54365,
        27.7469,
        26.530725,
        27.489225
      ],
      "leave_one_block_out_range_percent": [
        26.530725,
        27.7469
      ],
      "repeated_runs_at_least_three_values": []
    },
    {
      "group": "SE/CHX",
      "n_source_scan_rows": 50,
      "source_row_mean_percent": 30.10082,
      "source_row_median_percent": 29.9805,
      "source_row_sample_sd_percent_not_independent_tooth_sd": 7.453359830496388,
      "source_row_range_percent": [
        17.391,
        44.582
      ],
      "conditional_block_as_tooth_summary": {
        "n_worksheet_blocks": 5,
        "block_means_percent": [
          36.0322,
          24.8352,
          30.7214,
          29.912,
          29.0033
        ],
        "mean_percent": 30.10082,
        "sample_sd_of_block_means_percent": 4.016632462897247,
        "qualification": "Conditional worksheet-block nesting sensitivity; paper reports five teeth and ten scans per tooth, but no individual identity crosswalk is present. No donor count or independent replication is inferred from row blocks."
      },
      "leave_one_source_block_out_means_percent": [
        28.617975,
        31.417225,
        29.945675,
        30.148025,
        30.3752
      ],
      "leave_one_block_out_range_percent": [
        28.617975,
        31.417225
      ],
      "repeated_runs_at_least_three_values": []
    }
  ],
  "source_table2_reconciliation": [
    {
      "group": "ER",
      "published_mean_percent": 34.3,
      "published_sd_percent": 5.6,
      "rounded_block_mean_matches": true,
      "rounded_block_sd_matches": true,
      "qualification": "Numerical agreement supports this worksheet segmentation; it does not recover physical specimen or donor IDs."
    },
    {
      "group": "ER/CHX",
      "published_mean_percent": 33.5,
      "published_sd_percent": 4.7,
      "rounded_block_mean_matches": true,
      "rounded_block_sd_matches": true,
      "qualification": "Numerical agreement supports this worksheet segmentation; it does not recover physical specimen or donor IDs."
    },
    {
      "group": "SE",
      "published_mean_percent": 27.3,
      "published_sd_percent": 1.9,
      "rounded_block_mean_matches": true,
      "rounded_block_sd_matches": true,
      "qualification": "Numerical agreement supports this worksheet segmentation; it does not recover physical specimen or donor IDs."
    },
    {
      "group": "SE/CHX",
      "published_mean_percent": 30.1,
      "published_sd_percent": 4.0,
      "rounded_block_mean_matches": true,
      "rounded_block_sd_matches": true,
      "qualification": "Numerical agreement supports this worksheet segmentation; it does not recover physical specimen or donor IDs."
    }
  ],
  "etch_specific_CHX_descriptive_contrasts": [
    {
      "etch_mode": "ER",
      "contrast": "ER/CHX minus ER",
      "difference_of_source_means_percentage_points": -0.8444000000000003,
      "independent_block_deletion_contrast_range_percentage_points": [
        -4.348675,
        1.8731500000000025
      ],
      "deletion_combinations": 25,
      "qualification": "Delete one ten-row source block from each group, independently. This is a conditional record-sensitivity range, not a CI, matched-pair effect, actual tooth loss model or population effect."
    },
    {
      "etch_mode": "SE",
      "contrast": "SE/CHX minus SE",
      "difference_of_source_means_percentage_points": 2.8027999999999977,
      "independent_block_deletion_contrast_range_percentage_points": [
        0.8710750000000012,
        4.886499999999998
      ],
      "deletion_combinations": 25,
      "qualification": "Delete one ten-row source block from each group, independently. This is a conditional record-sensitivity range, not a CI, matched-pair effect, actual tooth loss model or population effect."
    }
  ],
  "SE_minus_ER_contrast_of_mean_differences_percentage_points": 3.647199999999998,
  "new_p_value_or_confidence_interval": null,
  "equivalence_established": false,
  "source_reported_nominal_cavity_depth_mm": 2,
  "actual_specimen_repair_depth_um": null,
  "thermal_cycles_before_OCT": 10000,
  "mechanical_fatigue_cycle_history": null,
  "baseline_OCT_before_aging": null,
  "depth_response_or_within_specimen_change": null,
  "source_reported_OCT_teeth_per_group": 5,
  "independent_donor_count": null,
  "cross_endpoint_specimen_pairing": null,
  "OCT_to_microtensile_correlation": null,
  "published_unlinked_tensile_table3_not_pooled": [
    {
      "group": "ER",
      "mean_MPa": 27.5,
      "source_sd_MPa": 2.9,
      "adhesive_cohesive_mixed_counts": [
        9,
        1,
        0
      ],
      "source_beams_n": 10
    },
    {
      "group": "ER/CHX",
      "mean_MPa": 26.7,
      "source_sd_MPa": 4.9,
      "adhesive_cohesive_mixed_counts": [
        9,
        1,
        0
      ],
      "source_beams_n": 10
    },
    {
      "group": "SE",
      "mean_MPa": 22.5,
      "source_sd_MPa": 5.2,
      "adhesive_cohesive_mixed_counts": [
        6,
        4,
        0
      ],
      "source_beams_n": 10
    },
    {
      "group": "SE/CHX",
      "mean_MPa": 13.1,
      "source_sd_MPa": 2.3,
      "adhesive_cohesive_mixed_counts": [
        9,
        0,
        1
      ],
      "source_beams_n": 10
    }
  ],
  "pretest_failures_or_unreported_losses": null,
  "full_native_restoration_and_finite_support_withdrawal_qualified": false,
  "assay_qualification": "Authors call this microleakage: proportion of selected cavity-floor width occupied by enhanced binary OCT signal after silver processing. It is not a measured fluid flux, universal leak-free classifier or full-depth material restoration metric.",
  "inputs_text_sha256": "7672be229d0532b67f1777499c71857f3099e28235c030e730f65fb6b0ad754f"
}